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real-time
PCR cyclers (4)
real-time
PCR cyclers (1)
real-time
PCR cyclers (2)
real-time
PCR cyclers (3)
The genesig q16 is designed to be the World’s
most affordable qPCR instrument. The unique
design uses no moving parts making it the first
solid state qPCR machine in the World. With a
footprint of only 12cm it is probably also the
smallest. Each of the 16-wells has an
individual excitation and detection source leading
to exceptional data quality and avoiding many of the
issues with a block based instrument. A
circular peltier element provides precise heating
and cooling as you would expect. The platform
is designed to accompany the genesig easy kit range;
a catalogue of over 400 qPCR based applied tests.
DNA testing - Everything Everyone
Everywhere
- The World's most affordable qPCR
machine
- Only Ł3995
- 16 wells
- Simple to use
- >400 DNA test kits available
- Food and Water testing
- Veterinary Diagnostics
- Human Infectious Disease Screening
- Biothreat Detection
- .... ... and more
With the Eco system, Real-Time PCR technology
is now within reach of individual researchers.
Large, expensive thermal cyclers that take up an
entire workspace are replaced with an affordable,
compact system and Netbook computer that fit easily
in any lab. Delivering unsurpassed data quality for
40-cycle runs in as little as 40 minutes, the Eco
system revolutionizes qPCR accessibility for both
new and experienced Real-Time PCR users.
The flexible Eco system is an open platform
that supports all chemistries and Real-Time PCR
applications, including absolute quantification by
standard curve, relative quantification using the
ΔΔCq method with support for multiple reference gene
normalization, allelic discrimination by end-point
fluorescence, and gene scanning and genotyping by
High Resolution Melt (HRM) curve analysis.
Every Eco system includes a Netbook computer
pre-installed with flexible, easy-to-use software
that integrates user control, real-time data
collection, and advanced data analysis. The software
conforms to MIQE (Minimum
Information for Publication of Quantitative
Real-Time PCR Experiments) guidelines, making
data analysis and submission for publication review
more efficient.
Eco software uses a unique icon-driven user
interface to simplify experimental design and setup.
Pre-set defaults for plate setup and thermal profile
are provided for the most commonly used experimental
protocols. Temperature and time for each protocol
step can easily be changed by click-and-drag action
with the mouse. Experiment templates can be
customized and saved for future use. All qPCR
chemistries and all standard Real-Time PCR
applications are supported, with High Resolution
Melt (HRM) analysis as a standard option.
qPCR Solutions by Analytik Jena
qTOWER3 Family by
Analytik Jena
The qTOWER3 family is series of real time PCR
thermal cyclers by Analytik Jena designed for the
routine lab work. Unrivaled temperature homogeneity,
the shortest scan times, unparalleled precision and
future-proof adaptability to new applications make
the qTOWER3 family an ideal addition for every lab.
There are three different models: The qTOWER3
standard version with a 96 well format sample block,
the qTOWER3 touch with an additional touch screen
for easy and intuitive control directly on the
system and the qTOWER3 84 including a 384 wells
sample block.
- Hands-on:
Stand-alone operation via integrated tablet
control (10“) and/or enhanced PC control
- Transparent:
No costs for license or updates (license-free)
- Universal:
Covering a broad range of analysis tools
from a simple overview of Ct values to ddCT
method and multi plate analysis
- Multilingual:
Available in multiple different languages
- Convenient:
12 available Color, FRET and Protein
Modules can be installed or exchanged within a
few minutes
- Future-proof:
Adaptable to new applications at any time by
adding filter modules
- Robust:
Patented high performance optical system
with an outstanding long-term warranty of 10
years!
- Efficient:
Short scan times of 6 seconds for the entire
plate, irrespective of the number of dyes
detected
- Innovative:
Novel light source with 4 robust LEDs (RGBW) –
no preheating time, long life-time
- Brillant:
Ideal illumination and detection of all
96 wells individually without edge effect due to
fiber optic shuttle (384 wells in qTOWER3 84)
- Fast: Heating
rates
of 8 °C/sec and cooling rates of 6 °C/sec
- Unrivaled:
Ideal temperature homogeneity and unmatched
control accuracy (± 0.1 °C)
- Precise:
The temperature difference from lane to
lane is the same; simple programming of even
gradient temperatures is possible with our
unique Linear Gradient Tool (LGT)
- Higher
Throughput: in combination with lab
automation solutions by Analytik Jena truly
automated workflows with incredibly high
throughput rates can be achieved
The PikoReal
Real-Time PCR System is designed to fit into your lab,
even when bench-top space is limited. Offering an
exceptionally small footprint this qPCR instrument is
ideal for personal use and light enough for field
applications.
PikoReal also delivers innovative features and
outstanding performance, and is part of the complete
qPCR workflow offered by Thermo Scientific that
includes, sample preparation, nucleic acid extraction,
DNA/RNA analysis and qPCR assays and reagents.
INSTRUMENT:
• Multiplexing up to 4 channels
• Factory calibrated fluorophores:
FAM, Yakima Yellow, HEX, ROX, Texas Red, Cy5 and SYBR
Green
• No need for re-calibration of
fluorophores
• LED based instrument, no lamp
change during lifetime of the instrument
• CCD camera captures all wells
simultaneously
• Fast instrument with ca. 1
min/cycle (ramp rate >5°C/s heating and 4.5°C/s
cooling)
SOFTWARE:
• Easy sample definition by using
innovative virtual pipetting
• Relative Quantification, Absolute
Quantification, Melting Analysis, High Resolution
Melting (HRM) and Allelic Discrimination
• License free software including
all analysis modules by default
Download the brochure
Request
a
demo
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48x48 Dynamic Array
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96x96 Dynamic Array
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Fluidigm’s BioMark 96x96
Dynamic Arrays
These
new
integrated fluidic circuits (IFCs) are
capable of performing 9,216 simultaneous
experiments without any pre-spotting and
with complete flexibility for the
researcher. In a word, they are
“revolutionary.” Flyer
The
96.96
Dynamic Arrays are at the heart of
Fluidigm’s BioMark™ Genetic Analysis System,
which delivers new efficiencies in Gene
Expression and Genotyping. Fluidigm products
enable and accelerate your Single Cell Gene
Expression, Copy Number Variation and
Absolute Quantitation research in completely
new ways.
See how the
competition stacks up against the 96x96
dynamic array:
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384-well
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96x96
Dynamic
Array
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| Master Mix |
46,000µL
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240µl
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| Primer-probe |
9,200µL
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480µl
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| Plates |
24
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1
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| Pipette steps |
18,432
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192
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*Comparison
based on 96 samples tested against 96
assays for a total of 9,216 data points
using a single 384-well system running
10ul total reactions and a single BioMark
system using the 96.96 Dynamic Array. |
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The WaferGen
SmartChip System enables profiling and validation
workflows on a single platform, by combining
high-throughput, cost-effective target discovery with
the sensitivity, precision, and dynamic range of
real-time PCR for validation studies.
Gene
Expression
Profiling - Discover More
Gene expression profiling of specific diseases
has become increasingly important in drug development.
Comparison of gene expression patterns between normal
and diseased patients or expression profiles in the
presence or absence of drugs leads to discovery of
genes or a set of genes that can be used in drug
development. This requires monitoring of tens,
hundreds or thousands of mRNAs in large numbers.
The WaferGen SmartChip System offers the
capability to achieve this level of throughput with a
high degree of accuracy.
MicroRNA
Profiling
- Comprehensive human microRNA profile on a single
chip
MicroRNAs (miRNA) are post-transcriptional
regulators of cell proliferation, tissue
differentiation, embryonic development, and apoptosis.
Specific miRNA expression profiles may be
characteristic of diseases or disease states and used
as biomarkers. The identification of miRNA profiles
has become important for streamlining drug development
processes. The comparison of miRNA patterns from
normal and disease samples; or contrasting miRNA
profiles of the same sample in the presence or absence
of a drug leads to a greater understanding of pathways
and mechanisms of action.
The WaferGen SmartChip System in conjunction with
the pre-validated SmartChip human miRNA panel, offers
researchers the ability to carry out comprehensive,
rapid miRNA profiling on their human samples simply,
cost-effectively, and accurately.
OpenArray
=>
now with Life Technologies
Imagine performing more than 3,000 assays
simultaneously. Imagine generating hundreds of
thousands of data points every day. With
OpenArray, it’s not just a possibility, it’s a
proven fact.
OpenArray represents a major breakthrough for
life science researchers, enabling massively
parallel, high quality nanoliter assays. It’s
ideal for low-volume solution-phase reactions
including analysis of genetic, genomic,
biochemical, and cellular samples.
Want to find out more? Just follow the links
and see how you can put OpenArray technology
to work for you.
For more information on specific
OpenArray technology products, click on
the appropriate link below:
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The OpenArray
Real-Time qPCR System enables nearly three
thousand real-time qPCR assays to be run on
a single OpenArray plate
Researchers can test one to 48
different samples against a wide array of
assays. The system enables flexibility in
experimental design in many research areas:
* Quantitative expression
analysis
* Pathogen detection
* Methylation studies
* Pathway analysis
* Infectious disease
studies
* Forensics
* Genetic identification
OpenArray SYBR real-time
qPCR
OpenArray® Real-Time qPCR System enables
nearly three thousand real-time qPCR assays to
be run on a single OpenArray plate. The
marriage of the OpenArray technology with the
popular SYBR® Green chemistry provides
researchers with a high density format that
not only saves time but also saves
money. With a highly flexible format and
nanoliter scale, the OpenArray platform allows
for easy adjustment of sample and assay
numbers, and enables you to generate more than
24,000 real-time qPCR data points per day,
increasing sample throughput while
significantly decreasing time and cost.
- Fast-Each run on the OpenArray
system cycles and images more than 9,000
reactions much higher throughput than
plate-based systems. What’s more, in a
typical 8-hour workday, one OpenArray
system performs multiple runs, helping you
zip through your studies.
- Flexible-You need to validate
microarray results anyway. Now you can use
one system for expression profiling,
biomarker identification, and screening
studies. Plus, the flexible format of the
OpenArray system allows you to customize
your own gene panel screen 100s of assays
or 100s of samples, it’s your choice.
- Economical-Only 33nL per reaction!
That is 150-fold less than the typical
384-well plate, which allows you to
conserve precious sample and reagents. And
the system is operated by a single user.
That adds up to significant labor and
material savings.
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BioGene
Thermal
Cycler Systems
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Patent
pending Integrated Heating Technology (IHT)
forms the basis of this system. It has long
been recognised that intra-sample variations
caused by thermal gradients within metal block
or air-heating systems causes differences in
the final product (quantity and quality). IHT
uses the concept of directly heating the
vessel containing the reaction mix and in
addition having a single, infrared temperature
sensor for each vessel to ensure truly
independent thermal control. Direct heating
also has a significant effect on thermal
transfer rates as does the ‘capillary’ design
of the reaction vessel (allows for a high
surface to volume ratio) both leading to
Ultra-Rapid thermal cycling. High
throughput, cleaner reaction products and the
ability to run reactions with different
thermal profiles are significant advantages of
this technology e.g. running gradients for
process optimisation, multiple different tests
on the same sample in diagnostic applications
where time to report results is critical and
high throughput screening. Synchrom
mannual synchron.pdf
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Patented Electrically
Conducting Polymer (ECP) Technology forms
the basis of this system. It has long been
recognised that intra-sample variations
caused by thermal gradients within metal
block or air-heating systems causes
differences in the final product (quantity
and quality).
ECP Technology uses the concept of directly
heating the vessel containing the reaction
mix and in addition having a single,
infrared temperature sensor for each vessel
to ensure truly independent thermal control.
Direct heating also has a significant effect
on thermal transfer rates as does the
‘capillary’ design of the reaction vessel
(allows for a high surface to volume ratio)
both leading to Ultra Rapid thermal cycling.
High throughput, cleaner reaction products
and the ability to run reactions with
different thermal profiles are significant
advantages of this technology e.g. running
gradients for process optimisation, multiple
different tests on the same sample in
diagnostic applications where time to report
results is critical and high throughput
screening.
InSyte uses leading edge technology to
ensure that the thermal performance is
matched by fast, sensitive optics. A
compact, high lifetime (10,000 hour)
solid-state laser provides an intense,
well-collimated pure light source at 473 nm
(compatible with all standard chemistries,
dyes and dye sets). A multichannel PMT
collects all emitted wavelengths between 520
and 720 nm-the system is not constrained by
use of filter sets to detect fixed bands of
emitted fluorescence. This allows the user
to ‘see the full picture’! High scan rates
(full plate read every 3 seconds) provide
good data sets for use in subsequent
analysis.
View InSyte technical document
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ULTRA-RAPID THERMAL CYCLING |
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UNIQUE 'Electrically Conducting
Polymer' (ECP) technology facilitates: |
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DIRECT heating to a
specially designed tube to allow rapid
thermal equilibration of reaction mix. |
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TRULY Independent temperature control
of each tube of the 96-MTP. Choose to run
completely different temperature profiles in
each tube! |
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FAST SENSITIVE,
photon counting optics. |
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COMPREHENSIVE DATA LOGGING/ANALYSES:
Embedded Graphical Control System enables
user-friendly empirical set up and complete
logging/analyses of data. |
Real-Time
PCR Cycler "DT-322" is intended for a
carrying out of polimerase chain reaction (PCR)
with a detection of an accumulation of PCR
products during an amplification (real -Time PCR).
DT-322 allows to carry out the qualitative and
quantitative PCR analysis excepting a stage of the
electrophoresis of PCR products in an agarose gel.
The device is designed for simultaneous analysis
of up to 32 samples. A thermocycler and an optical
system of a fluorescence detection are united in
this device. All data of the last
amplification are recording into a private memory
of the PCR Cycler and can be read out even after a
current interruption occurred during an
amplification. After a restoring of a power supply
the amplification program will be continued, and
the moment of interruption, its duration and a
block temperature in the moment of interruption
will be recorded. A turning off or a hanging of
external computer does not result in PCR
termination since the process control is managed
by the private memory of the device that does not
depend on a computer.
Brochure and
technical parameters (PDF)
TL998 - Real-time Quantitative
PCR Detecting System
http://www.medtl.com/english/ckcp.asp?id=8
The
TL998
System provides an efficiency and high-speed
solution for PCR analysis. Real-time PCR delivers
increased sensitivity and a wider dynamic range more
rapidly than traditional PCR. TL998 gives you a
choice of quantitation methods for gene expression.
It is very important in curative evaluation. The
TL998 system ideally suited to meet the
high-throughput requirements of today's drug
discovery process. The TL998 is useful for life
science research, and it is innovative and
pioneering products for the prevention, diagnosis,
evaluation and monitoring of diseases.
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LineGene3310/3320
real-time PCR delection system is
up-to-date product based on linegene. the
redesigned LineGene3310/3320 recieves the
mature design of heating block, control
system and detection system, but it was
designed more completely and detection
system,but it was designde more completely
and the heating and cooling rate reached
6C/s. it is more compact and firmly
inconstruction.the performance is highly
approved,but the apperance becomes smaller
and simple.
LineGene3310
is mainly recommended to customers in
clinic inspection,commercial
inspection,blood bank and so on.meanwhile,
LineGene3320 is mainly recommended to
cusromer im scientific research institute
and vadvantage clinic inspection.
http://www.bioer.com.cn/E/productsXx.asp?pid=4
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Line-Gene-K is
the newest system in Bioer's range of PCR
detection systems. It features more
advanced implementations of Peltier and
fiber optic technology and a new direct
current power system.
The
new instruments share the Peltier effect
and fiber optic design features that
provide the exceptional accuracy and
stability of the Line-Gene instruments.The
new units offer improved
uniformity,stability and accuracy by
utilizing a constant-current power supply
and an advanced multi-point temperature
control module.The Line-Gene.K has
improved temperature control and more
uniform heating throughout the sample
block to improve the accuracy of PCR
detection.
The
Line-Gene.K series is available in a range
of automated and manual models with the
ability to handle one, two, three or four
combinations of excitation and emission
wavelengths.
http://www.bioer.com.cn/E/productsXx.asp?pid=3
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Line Gene is a
complete real-time PCR detection system
that can detect and quantitate nucleic
acid sequences by monitoring fluorescence
value during the PCR process. With
innovative design on hardware and
software, the unit is an ideal tool for
research use in the field of gene
analysis.
Features:
• Long life blue LED light Source
• Extremely sensitive PMT detection
module
• Sandwich thermo-electronic (TE)
module
• Easy yet powerful software
• Data Export
http://www.bioer.com.cn/E/productsXx.asp?pid=1
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Line Gene II
Real-time PCR Detection System is up-to-date
product based on Line-gene. By using the
advanced optical fiber conducting technique,
the unit has strong sensitivity and
reliability when detects the fluorescence.
At the same time, it inherits all merits of
Line-gene so to realize speedy and accurate
PCR detection. What's more, the powerful
software provides multiple channels
fluorescence detection with four kinds of
dyes at the same time. And the testing
result of samples can be analyzed and
compared by groups so that many functions,
such as absolute quantitative, comparative
quantitative, SNPs and melting curve
analysis, can be accomplished.
Multiple
Applications:
TaqMan probe; SYBR Green I; Molecular
beacons, FAM, HEX, TAMRA, TEXASRED, ROX and
so on.
http://www.bioer.com.cn/E/productsXx.asp?pid=2
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ExicyclerTM 96
Real-Time Quantitative Thermal Block
http://eng.bioneer.com/bioneer.html?!products/Exicycler.html
ExicyclerTM
Real
Time Thermal Block and its operation
software is optimized for applications such
as quantification of gene expression,
genotyping, counting bacterial/viral
loads, melt-curve analysis and validation of
microarray results. Exicycler is also
capable of measuring mutual interactions
between two molecules, such as
protein-protein and protein-ligand, using
fluorescence resonance energy transfer
(FRET). In addition, the sensitivity,
accuracy and system integration-ready design
of Exicycler makes it ideal for
high-throughput analysis.
http://eng.bioneer.com/bioneer.html?%21Diagnostics/DianosticIns_Exicycler.html
A battery-powered
notebook thermal cycler for rapid
multiplex real-time
PCR
analysis
Belgrader P, Young S, Yuan B, Primeau
M, Christel LA, Pourahmadi F, Northrup MA.
Anal Chem. 2001 Jan 15;73(2): 286-289.
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